Graviola for Cancer Treatment: Benefits and Risks
Graviola (Annona muricata), also called soursop, is a fruit tree that grows in tropical forests. People have long used fruits, roots, seeds, and leaves to treat various ailments, including cancer.
Modern scientists have been studying the plant for 50 years. They see a potential promise in Graviola. They found that it kills cancer cells in test tubes and animal studies.
do not yet know if it works as a cure for cancer in humans.
How Does It Work?
Graviola contains hundreds of chemicals called acetogenins (ACGs). In a laboratory test, ACGs kill many types of cancer cells without harming healthy ones. They can even treat tumors that have not yet responded to cancer treatment.
ACGs seem to work in different ways to kill, prevent, or fight different types of cancer. Methods include:
Cell death. Usually, old or damaged cells die naturally, a process called apoptosis. Cancer cells often find a way to avoid this and survive. Graviola leaf extracts may force cancer cells to pass through normal cell death.
Prevent metastasis. It is also called the spread of cancer. Laboratory studies found that Graviola extract stopped cancer cells from growing and growing metastasizing.
Clicking icons. Cells receive messages inside and outside the cell. Signal modes transmit messages. A mistake in one of these methods can lead to cancer. Graviola blocks the mechanisms that control the growth and life cycle of cancer cells.
ATP. All the cells in your body use a compound called adenosine triphosphate (ATP) for energy. When Graviola blocks ATP from cancer cells, the cells die.
What the Research Says
Scientists have studied Graviola for many types of cancer. The findings of the lab study are promising. But they have not tested Graviola in humans to know what the results will be.
Breast cancer. In another study, the Graviola leaf extracted wrinkled lungs from mice. Some studies have looked at the effect of Graviola fruit extract on a protein called epidermal growth factor receptor (EGFR). This protein sits on top of the cells and helps them grow and divide. Some breast cancer cells have a lot of EGFR. Cells grow rapidly and are difficult to manage. Graviola inhibits the growth of these cells.
Liver cancer. In several studies, the release of Graviola caused cell death in liver cancer cells.
Lung cancer. Graviola leaf extract stopped the growth cycle of lung cancer cells.
Pancreatic cancer. Powdered Graviola leaves and stems caused cell death in pancreatic cancer cells. Graviola also blocked signaling mechanisms that help pancreatic tumors.
What did the Research Say? Is It Possible?
South Americans and Africans use Graviola for food and medicine. The fruit tastes like pineapple. You can also buy Graviola pills and liquids online and at natural food stores. No one knows the best dose or how safe it is. Potential dangers from Graviola may include:
Nerve damage. Some laboratory animals experienced tremors and other movement problems such as symptoms of Parkinson’s disease.
Low blood pressure. Graviola can lead to lower blood pressure in animals and humans. This can cause problems if you already have low blood pressure or medication.
Low blood sugar. Graviola can be dangerous if you tend to have low blood sugar (hypoglycemia) or take diabetes drugs.
Error testing. Graviola can interfere with nuclear imaging because it prevents your body from absorbing the radioactive material used in experiments. It can also interfere with your blood pressure reading or your blood sugar test.
You should not use Graviola instead of your regular cancer treatment. If you would like to add it to a medication you have already taken, talk to your doctor.
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